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KMID : 0358419950380122359
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Korean Journal of Obstetrics and Gynecology
1995 Volume.38 No. 12 p.2359 ~ p.2364
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Histopathologic Analysis of Diagnosis from Colposcopically Directed Biopsy and the Surgical Specimen by Conization or Hysterectomy
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서호석
신재철/문준/허준용/박용균/조수용/주갑순
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Abstract
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Two hunderd and fifty two patients taken colposcopically directed biopsy were performed conization, simple hysterectomy or radical hysterectomy depending on their current disease status.
This study was designed to compare the rate of agreement or disagreement with the diagnosis of colposcopically directed biopsy and surgical specimen. The results of colposcopically directed biopsy were analyzed with regard to the histopathologic
findings of the surgical specimen.
The complete diagnostic agreement of colposcopically directed biopsy with surgical specimen was 77.8% (196 of 252) and the diagnostic accuracy less than one degree was 97.6%(246/252). Assuming that the histopahologic diagnosis of the surgical
specimen
is finally correct, the false positive rate and false negative rate of the directed biopsy were 2.1%(5/135) and 0.9%(1/108) respectively. There was no case in which invasive cancer was missed through colposcopically directed biopsy.
So we concluded that the colposcopically directed biopsy can take place of conization in the diagnosis of cervical neoplasia and considered that the histopathologic discrepancy between the colposcopically directed biopsy and the surgical specimen
of
cervix would be probable cause by inappropriate direction and entire resection of the lesions by the biopsy itself.
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KEYWORD
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